AUTHOR=Wu Chaofei , Liu Hongxin , Li Juan , Xiao Hong-Ping , Li Xinhua , Jiang Jun 

TITLE=Chiral 1H NMR of Atropisomeric Quinazolinones With Enantiopure Phosphoric Acids

JOURNAL=Frontiers in Chemistry

VOLUME=6

YEAR=2018

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2018.00300

DOI=10.3389/fchem.2018.00300

ISSN=2296-2646

ABSTRACT=<p>A chiral phosphoric acid promoted enantioselective NMR analysis of atropisomeric quinazolinones was described, in which a variety of racemic arylquinazolinones such as afloqualone and IC-87114 were well recognized with up to 0. 21 ppm ΔΔδ value. With this method, the optical purities of different non-racemic substrates can be fast evaluated with high accuracy.</p>