AUTHOR=Gawande Manoj B., Disale Shamrao , Kale Sandip , Abraham George , Kahandal Sandeep , Sawarkar Ashish 

TITLE=A Sustainable and Efficient Synthesis of Benzyl Phosphonates Using PEG/KI Catalytic System

JOURNAL=Frontiers in Chemistry

VOLUME=4

YEAR=2016

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2016.00035

DOI=10.3389/fchem.2016.00035

ISSN=2296-2646

ABSTRACT=<p>An efficient and expedient protocol for the synthesis of benzyl phosphonates using KI/K<sub>2</sub>CO<sub>3</sub> as a catalytic system and PEG-400 as benign solvent has been developed. The reaction proceeds smoothly at room temperature achieving excellent selectivity and yield of the corresponding products. The combination of PEG-400, KI, and K<sub>2</sub>CO<sub>3</sub> in this reaction avoids the need of volatile/toxic organic solvents and reactive alkali metals or metal nanoparticles/hydrides. We believe that this benign combination (PEG-400 and KI) could be used for other related organic transformations.</p>