AUTHOR=Hervé Gwénaëlle , Len Christophe 

TITLE=Aqueous microwave-assisted cross-coupling reactions applied to unprotected nucleosides

JOURNAL=Frontiers in Chemistry

VOLUME=3

YEAR=2015

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2015.00010

DOI=10.3389/fchem.2015.00010

ISSN=2296-2646

ABSTRACT=<p>Metal catalyzed cross-coupling reactions have been the preferred tools to access to modified nucleosides (on the C5-position of pyrimidines and on the C7- or C8-positions of purines). Our objective is to focus this mini-review on the Suzuki-Miyaura and on the Heck cross-couplings of nucleosides using microwave irradiations which is an alternative technology compatible with green chemistry and sustainable development</p>