Frontiers in Cellular Neuroscience

Original Research

Published on 16 Sep 2025

Boldine as a neuroprotective agent against motor neuron degeneration in models of amyotrophic lateral sclerosis

in Cellular Neuropathology

Carlos A. Toro
Wei Zhao
Patricio Garcia Silva
Daniela Retamal-Santibáñez
Fabiola Rojas
Jiangping Pan
Nicholas Johnson
Yorley Duarte
Christopher P. Cardozo
Juan C. Sáez

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1640590

346 views

Original Research

Published on 15 Sep 2025

Distinct reduction in relative microglial glucose uptake compared to astrocytes and neurons upon isolation from the brain environment

in Non-Neuronal Cells

Sebastian T. Kunte
Johannes Gnörich
Philipp Beumers
Laura M. Bartos
Stephan Wagner
Karin Wind-Mark
Adrien Holzgreve
Dennis Pötter
Rudolf A. Werner
Sibylle Ziegler

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1572431

431 views

Original Research

Accepted on 12 Sep 2025

Dual Role of Lyz2-positive Myeloid Cells in Traumatic Brain Injury: Acute Anti-Inflammatory Effects versus Chronic Neurological Deterioration

in Cellular Neuropathology

Huazheng Yan
yiwan Fang
shiyu Zhou
jianxiong Gao
mingming Bian
yaomei Xü
lin Zhang
nan Zhang
He-Zuo Lü

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1642410

240 views

Original Research

Accepted on 12 Sep 2025

THC Reverses SIV-Induced Senescence in Astrocytes: Possible Compensatory Mechanism Against HIV Associated Brain Injury?

in Cellular Neuropathology

Alison Van Zandt
Miranda Horn
Tiffany Peterson
Sarah Dickinson
Elise Frost
Andrew MacLean

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1642917

203 views

Original Research

Published on 12 Sep 2025

Establishment of human Leber’s hereditary optic neuropathy model using iPSC-derived retinal organoids

in Cellular Neuropathology

Kota Aoshima
Yuya Takagi
Michinori Funato
Yoshiki Kuse
Shinsuke Nakamura
Masamitsu Shimazawa

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1635775

719 views

Original Research

Accepted on 10 Sep 2025

Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury

in Cellular Neuropathology

Lei Yan
Xun Zhou
Qianqiu Li
Hongxiang Hong
Chunshuai Wu
Yong-Jing Gao
Guanhua Xu
Zhiming Cui

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1622825

383 views

Brief Research Report

Accepted on 10 Sep 2025

Brain-derived neurotrophic factor prevents LPS-induced dysregulation of GABAergic interneuron markers in mouse hippocampus

in Cellular Neuropathology

Sara Rezaei
Mounira Banasr
Thomas Prevot
Yashika Bansal
Erica Vieira
Etienne Sibille

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1675003

345 views

Review

Published on 10 Sep 2025

Alzheimer’s disease: where do we stand now and what are the strategic interventions?

in Cellular Neuropathology

Andrea González
Stephanie Geywitz
Ricardo B. Maccioni

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1655342

714 views

Review

Published on 10 Sep 2025

Schwann cells in the inner ear: development, disease, and regeneration

in Cellular Neuropathology

Drew J. Montigny
Judith S. Kempfle

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1662274

625 views

Original Research

Accepted on 08 Sep 2025

A Mutational Hotspot in TUBB2A Associated with impaired Heterodimer Formation and severe Brain Developmental Disorders

in Cellular Neuropathology

Gabriele Di Pasquale
Jacopo Colella
Carola Pia Di Cataldo
MIGUEL A. SOLER
Sara Fortuna
Emma Mizrahi-Powell
Mathilde Nizon
Benjamin COGNE
Valentina Turchetti
Giuseppe Mangano

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1664953

439 views

Methods

Published on 08 Sep 2025

A customized affordable multiplexed immunofluorescence method visualizes early changes in the mouse brain microenvironment upon laser cytoreduction

in Cellular Neuropathology

Santhosh Shanmugam Anandhan
Jeremy Spence
Farhana Begum
Nimrat Kaur
Dana Henderson
Sabine Hombach-Klonisch
Thomas Klonisch

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1553058

678 views

Original Research

Accepted on 05 Sep 2025

Rotenone accelerates endogenous α-synuclein spreading and enhances neurodegeneration in an intra-striatal α-synuclein preformed fibril (PFF) injected mouse model of Parkinson's Disease

in Non-Neuronal Cells

Engila Khan
Nada Radwan
Mustafa T Ardah
Tohru Kitada
M Emdadul Haque

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1624593

566 views

Original Research

Published on 05 Sep 2025

Growth hormone reduces retinal inflammation and preserves microglial morphology after optic nerve crush in male rats

in Cellular Neuropathology

Jerusa E. Balderas-Márquez
David Epardo
Lourdes Siqueiros-Márquez
Martha Carranza
Maricela Luna
José Luis Quintanar
Carlos Arámburo
Carlos G. Martínez-Moreno

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1636399

837 views

Review

Accepted on 03 Sep 2025

Spatiotemporal crosstalk among mitochondrial dynamics, NLRP3 1 inflammasome activation, and histone lactylation drives α-synuclein pathology in 2 prodromal Parkinson's disease

in Cellular Neuropathology

Peizhu Lv
Xia Chen
Shiping Liu
Yu Zhang
Yulin Wang
Shun Wang
Yan Bai

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1636185

589 views

Original Research

Published on 03 Sep 2025

Nodal Na+ and Ca2+ flux dynamics in cortical myelinated axons

in Cellular Neurophysiology

Oron Kotler
Kenichi Miyazaki
Yana Khrapunsky
William N. Ross
Ilya A. Fleidervish

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1662730

857 views

Original Research

Published on 03 Sep 2025

Early olfactory dysfunction in experimental autoimmune encephalomyelitis reflects transient brain barrier breach and initiation of neuroinflammation in the olfactory bulb

in Cellular Neuropathology

Andjela Stekic
Milorad Dragic
Ivana Stevanovic
Marina Zaric Kontic
Marija Adzic Bukvic
Sanja Dacic
Milica Ninkovic
Nadezda Nedeljkovic

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1656777

835 views