AUTHOR=Yu Luting , Su Xiaojuan , Li Shiping , Zhao Fengyan , Mu Dezhi , Qu Yi 

TITLE=Microglia and Their Promising Role in Ischemic Brain Injuries: An Update

JOURNAL=Frontiers in Cellular Neuroscience

VOLUME=14

YEAR=2020

URL=https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2020.00211

DOI=10.3389/fncel.2020.00211

ISSN=1662-5102

ABSTRACT=<p>Ischemic brain injuries are common diseases with high morbidity, disability, and mortality rates, which have significant impacts on human health and life. Microglia are resident cells of the central nervous system (CNS). The inflammatory responses mediated by microglia play an important role in the occurrence and development of ischemic brain injuries. This article summarizes the activation, polarization, depletion, and repopulation of microglia after ischemic brain injuries, proposing new treatment strategies for such injuries through the modulation of microglial function.</p>