AUTHOR=Krauth Nathalie , Khalil Valentina , Jariwala Meet , Mermet-Joret Noemie , Vestergaard Anne-Katrine , Capogna Marco , Nabavi Sadegh 

TITLE=TRACE: An Unbiased Method to Permanently Tag Transiently Activated Inputs

JOURNAL=Frontiers in Cellular Neuroscience

VOLUME=14

YEAR=2020

URL=https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2020.00114

DOI=10.3389/fncel.2020.00114

ISSN=1662-5102

ABSTRACT=<p>A fundamental interest in circuit analysis is to parse out the synaptic inputs underlying a behavioral experience. Toward this aim, we have devised an unbiased strategy that specifically labels the afferent inputs that are activated by a defined stimulus in an activity-dependent manner. We validated this strategy in four brain circuits receiving known sensory inputs. This strategy, as demonstrated here, accurately identifies these inputs.</p>