AUTHOR=Wozny Christian , Beed Prateep , Nitzan Noam , Pössnecker Yona , Rost Benjamin R. , Schmitz Dietmar TITLE=VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons JOURNAL=Frontiers in Cellular Neuroscience VOLUME=12 YEAR=2018 URL=https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2018.00337 DOI=10.3389/fncel.2018.00337 ISSN=1662-5102 ABSTRACT=

The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.