AUTHOR=Cataldi Samuela , Arcuri Cataldo , Hunot Stéphane , Mecca Carmen , Codini Michela , Laurenti Maria E. , Ferri Ivana , Loreti Elisabetta , Garcia-Gil Mercedes , Traina Giovanna , Conte Carmela , Ambesi-Impiombato Francesco S. , Beccari Tommaso , Curcio Francesco , Albi Elisabetta TITLE=Effect of Vitamin D in HN9.10e Embryonic Hippocampal Cells and in Hippocampus from MPTP-Induced Parkinson’s Disease Mouse Model JOURNAL=Frontiers in Cellular Neuroscience VOLUME=12 YEAR=2018 URL=https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2018.00031 DOI=10.3389/fncel.2018.00031 ISSN=1662-5102 ABSTRACT=
It has long been proven that neurogenesis continues in the adult brains of mammals in the dentatus gyrus of the hippocampus due to the presence of neural stem cells. Although a large number of studies have been carried out to highlight the localization of vitamin D receptor in hippocampus, the expression of vitamin D receptor in neurogenic dentatus gyrus of hippocampus in Parkinson’s disease (PD) and the molecular mechanisms triggered by vitamin D underlying the production of differentiated neurons from embryonic cells remain unknown. Thus, we performed a preclinical