AUTHOR=Goo Yong Sook , Park Dae Jin , Ahn Jung Ryul , Senok Solomon S. TITLE=Spontaneous oscillatory rhythms in the degenerating mouse retina modulate retinal ganglion cell responses to electrical stimulation JOURNAL=Frontiers in Cellular Neuroscience VOLUME=9 YEAR=2016 URL=https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2015.00512 DOI=10.3389/fncel.2015.00512 ISSN=1662-5102 ABSTRACT=
Characterization of the electrical activity of the retina in the animal models of retinal degeneration has been carried out in part to understand the progression of retinal degenerative diseases like age-related macular degeneration (AMD) and retinitis pigmentosa (RP), but also to determine optimum stimulus paradigms for use with retinal prosthetic devices. The models most studied in this regard have been the two lines of mice deficient in the β-subunit of phosphodiesterase (