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EDITORIAL article
Front. Cell. Infect. Microbiol.
Sec. Veterinary and Zoonotic Infection
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1599457
This article is part of the Research TopicViral Diseases in SwineView all 8 articles
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Advances in diagnostic tools are pivotal for early disease control. Cao et al. (2024) present a CRISPR/Cas12a-based assay integrated with enzymatic recombinase amplification (ERA) for ASFV detection, achieving a sensitivity of 10 copies per reaction. This method offers a portable, field-deployable solution, crucial for resource-limited settings. Song et al. (2024) further demonstrate the utility of recombinase-aided amplification (RAA) combined with lateral flow dipsticks for Senecavirus A, enabling visual detection within 17 minutes. These studies exemplify the potential of isothermal amplification technologies to revolutionize point-ofcare diagnostics.Vaccines remain the cornerstone of swine disease prevention. Chen et al. ( 2024) review the promise of multi-epitope vaccines, leveraging immunoinformatics to design constructs targeting conserved regions of variable pathogens like ASFV and PRRSV. Xie et al. (2024) extend this concept by evaluating recombinant adenovirus vaccines expressing GP3 and GP5 proteins of NADC34-like PRRSV, demonstrating robust humoral and cellular immune responses in pigs. These findings highlight the importance of subunit vaccines and adjuvant strategies in combating antigenically diverse viruses.The identification of novel antiviral compounds is equally critical. Li et al. ( 2025) explore chebulinic acid's dual inhibitory effects on PEDV entry and viral main protease, offering a natural product-based therapeutic candidate. This work underscores the potential of phytochemicals in combating coronaviruses, aligning with global efforts to discover sustainable antiviral agents. This Research Topic serves as a testament to the interdisciplinary nature of swine disease research. By bringing together insights from virology, immunology, and epidemiology, it paves the way for a more resilient swine industry. We extend our gratitude to all authors and reviewers for their contributions, which collectively strengthen our capacity to tackle these pressing challenges.
Keywords: Swine Diseases, Vaccine, drug, diagnostics, antimicrobial resistance, mechanisms
Received: 25 Mar 2025; Accepted: 14 Apr 2025.
Copyright: © 2025 Liu, Hameed and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ke Liu, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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