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EDITORIAL article

Front. Cell. Infect. Microbiol.
Sec. Molecular Bacterial Pathogenesis
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1557057
This article is part of the Research Topic Metabolomics in Bacterial Infections View all 5 articles

Editorial: Metabolomics in Bacterial Infections

Provisionally accepted
Vijay Soni Vijay Soni 1*Aditya Upadhyay Aditya Upadhyay 2Yong Zhang Yong Zhang 3
  • 1 Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, New York, United States
  • 2 Hospital for Special Surgery, New York, United States
  • 3 State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Jilin University, Changchun, Hebei Province, China

The final, formatted version of the article will be published soon.

    and represent the best measure to understand the pathogenesis. In this context, metabolomics has emerged as a powerful tool to interpret complex and dynamic biochemical changes. This approach provides valuable insights into bacterial physiology, virulence, and host immune responses, offering new directions for therapeutic development. The aim of this Research Topic, Metabolomics in Bacterial Infections, was to compile various research articles, methods, and reviews on host-pathogen metabolic interactions, including their modulation and regulation, role in virulence, potential as biomarkers, and promise for novel therapeutic development. We have curated four manuscripts that provide novel insights into host responses to Coxiella burnetii infection, metabolic changes during enteric infections and their impact on gut dysbiosis, the genotype-serotype relationship of Group B Streptococcus, and a review of various hostpathogen metabolic changes following Legionella infection.

    Keywords: Metabolomics, host pathogen interaction, Metabolism, Bacterial metabolomis, system biology

    Received: 07 Jan 2025; Accepted: 22 Jan 2025.

    Copyright: © 2025 Soni, Upadhyay and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Vijay Soni, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, 10021, New York, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.