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REVIEW article
Front. Cell. Infect. Microbiol.
Sec. Intestinal Microbiome
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1521754
This article is part of the Research Topic Influence of Maternal Dietary Patterns on Offspring Gut Microbiome and Immunity View all 3 articles
Unraveling the role of the gut microbiome in pregnancy disorders: insights and implications
Provisionally accepted- West China Second University Hospital, Sichuan University, Chengdu, China
The gut microbiota is the collective term for the microorganisms that reside in the human gut. In recent years, advances in sequencing technology and bioinformatics gradually revealed the role of gut microbiota in human health. Dramatic changes in the gut microbiota occur during pregnancy due to hormonal and dietary changes, and these changes have been associated with certain gestational diseases such as preeclampsia (PE) and gestational diabetes mellitus (GDM). Modulation of gut microbiota has also been proposed as a potential treatment for these gestational diseases. The present article aims to review current reports on the association between gut microbiota and gestational diseases, explore possible mechanisms, and discuss the potential of probiotics in gestational diseases. Uncovering the link between gut microbiota and gestational diseases could lead to a new therapeutic approach.
Keywords: Gut Microbiota, Preeclampsia, Insulin Resistance, Probiotics, postpartum depression, gestational diabetes mellitus
Received: 02 Nov 2024; Accepted: 20 Feb 2025.
Copyright: © 2025 Xie, Chen, Shan, Pan and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yayi Hu, West China Second University Hospital, Sichuan University, Chengdu, China
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