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ORIGINAL RESEARCH article
Front. Cell. Infect. Microbiol.
Sec. Clinical Infectious Diseases
Volume 14 - 2024 |
doi: 10.3389/fcimb.2024.1497965
This article is part of the Research Topic Neglected Tropical Diseases: Drug Targets, and Potential Treatments View all articles
Modulation of Metabolic Pathways and EndMT Inhibition by a Traditional Chinese Herbal Formula in the Treatment of High-Risk Infections
Provisionally accepted- 1 Shenzhen Hospital, Beijing University of Chinese Medicine, Shenzhen, China
- 2 Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China
- 3 Shenzhen Hospital of Beijing University of Traditional Chinese Medicine, Shenzhen, China
- 4 Shenzhen SMQ Group Medical Laboratory, Shenzhen, China
Background: Herbal products have long been utilized as remedies for various disease conditions, including infections. This study investigates the therapeutic mechanism of a traditional Chinese herbal combination in treating high-risk HPV infections. Methods:The herbal formula was prepared using common herbs: dry Millettia speciosa, Guanzhong (a spermatophyte), Sarsaparilla, White Fruit, and Cockscomb Flower. Eight female patients diagnosed with high-risk HPV were enrolled from January to September
Keywords: Combination of Chinese Herb, HPV infection, Metabolomics, endothelialto-mesenchymal transition (EndMT), Traditional Chinese Medicine
Received: 18 Sep 2024; Accepted: 28 Oct 2024.
Copyright: © 2024 You, Bu, Chen, Sun, Suyang, Feng and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hailing You, Shenzhen Hospital, Beijing University of Chinese Medicine, Shenzhen, China
Kailai Bu, Guangzhou University of Chinese Medicine, Guangzhou, 510006, Guangdong Province, China
Liping Chen, Shenzhen Hospital of Beijing University of Traditional Chinese Medicine, Shenzhen, China
He Sun, Shenzhen Hospital of Beijing University of Traditional Chinese Medicine, Shenzhen, China
Wangao Suyang, Shenzhen SMQ Group Medical Laboratory, Shenzhen, China
Gaofei Feng, Shenzhen Hospital of Beijing University of Traditional Chinese Medicine, Shenzhen, China
Yuan Chen, Shenzhen Hospital of Beijing University of Traditional Chinese Medicine, Shenzhen, China
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