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REVIEW article

Front. Cell. Infect. Microbiol.
Sec. Virus and Host
Volume 14 - 2024 | doi: 10.3389/fcimb.2024.1460604
This article is part of the Research Topic Virus-Induced Autophagy in Host Cells During Viral Infections View all articles

Effect of natural products on host cell autophagy induced by Influenza A virus infection

Provisionally accepted
Xiaopan Liu Xiaopan Liu *Qingsen Wang Qingsen Wang
  • College of Veterinary Medicine, Yangzhou University, Yangzhou, China

The final, formatted version of the article will be published soon.

    Influenza A virus (IAV) can cause seasonal epidemics and global pandemics, posing serious threats to public health, making a deeper understanding of its biological characteristics and effective countermeasure strategies essential. Autophagy not only maintains cellular homeostasis but also plays an important role in host defence against IAV infection. However, the relationship between IAV and autophagy is complex, and effective antiviral drugs are not yet available. Natural products have shown excellent potential in disease control due to their diversity and multi-targeting. This review focuses on the relationship between IAV and autophagy and discusses the potential of targeting autophagic pathways for the development of new antiviral therapies. Particularly, the use of plant extracts as autophagy modulators has garnered attention due to their non-toxic nature and cost-effectiveness, which provides strong support for the development of future antiviral drugs that can help to inhibit viral infections and slow down disease progression.

    Keywords: Influenza A virus, Autophagy, Plant Extracts, viral infections, Antiviral therapies

    Received: 06 Jul 2024; Accepted: 30 Aug 2024.

    Copyright: © 2024 Liu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xiaopan Liu, College of Veterinary Medicine, Yangzhou University, Yangzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.