Skip to main content

REVIEW article

Front. Cell. Infect. Microbiol.
Sec. Clinical Microbiology
Volume 14 - 2024 | doi: 10.3389/fcimb.2024.1402932
This article is part of the Research Topic Value of a multidisciplinary approach for modern diagnosis of infectious diseases View all 9 articles

Aptamers: Precision Tools for Diagnosing and Treating Infectious Diseases

Provisionally accepted
Rajalakshmi Naresh Rajalakshmi Naresh B U. Srivisanth B U. Srivisanth SWATHI SUJITH SWATHI SUJITH ANUSREE SAJEEVAN ANUSREE SAJEEVAN Shobana Rajaramon Shobana Rajaramon HELMA DAVID HELMA DAVID *Adline Princy Solomon Adline Princy Solomon *
  • Quorum Sensing Laboratory, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India

The final, formatted version of the article will be published soon.

    Infectious diseases represent a significant global health challenge, with bacteria, fungi, viruses, and parasitic protozoa being significant causative agents. The shared symptoms among diseases and the emergence of new pathogen variations make diagnosis and treatment complex. Conventional diagnostic methods are laborious and intricate, underscoring the need for rapid, accurate techniques. Aptamer-based technologies offer a promising solution, as they are cost-effective, sensitive, specific, and convenient for molecular disease diagnosis. Aptamers, which are single-stranded RNA or DNA sequences, serve as nucleotide equivalents of monoclonal antibodies, displaying high specificity and affinity for target molecules. They are structurally robust, allowing for long-term storage without substantial activity loss. Aptamers find applications in diverse fields such as drug screening, material science, and environmental monitoring. In biomedicine, they are extensively studied for biomarker detection, diagnostics, imaging, and targeted therapy. This comprehensive review focuses on the utility of aptamers in managing infectious diseases, particularly in the realms of diagnostics and therapeutics.

    Keywords: aptamers, SELEX, biosensor, Therapeutics, diagnosis, Bacteria, virus, infectious disease

    Received: 18 Mar 2024; Accepted: 03 Sep 2024.

    Copyright: © 2024 Naresh, Srivisanth, SUJITH, SAJEEVAN, Rajaramon, DAVID and Solomon. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    HELMA DAVID, Quorum Sensing Laboratory, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India
    Adline Princy Solomon, Quorum Sensing Laboratory, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.