AUTHOR=Morgado Debora Salgado , Castro Rodolfo , Ribeiro-Alves Marcelo , Corrêa-Moreira Danielly , Silva Júlio Castro Alves de Lima e , Menezes Rodrigo Caldas , Oliveira Manoel Marques Evangelista 

TITLE=Systematic review of literature to evaluate global distribution of species of the Sporothrix genus stored in culture collections

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=14

YEAR=2024

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1382508

DOI=10.3389/fcimb.2024.1382508

ISSN=2235-2988

ABSTRACT=<sec><title>Introduction</title><p>Sporotrichosis is a subcutaneous mycosis caused by fungi of the genus <italic>Sporothrix</italic> sp. Phenotypic and genotypic differences have been associated with their geographic distribution, virulence, or clinical manifestation of sporotrichosis. In the past decade, the interest in identifying species of the <italic>Sporothrix</italic> sp. has been increasing, due to its epidemiological importance and, in consequence, is important to know how to preserve them for future studies, in culture collection.</p></sec><sec><title>Aims</title><p>The purposes of this study were to analyze the global distribution of environmental isolates and/or causal agents of sporotrichosis identified by polyphasic taxonomy, with mandatory use of molecular identification, and to evaluate the percentages and distribution of isolates stored in culture collections.</p></sec><sec><title>Methods</title><p>A systematic review of articles on animal and human sporotrichosis and/or environmental isolation of the fungus, from 2007 to 2023, was done. Results: Our results demonstrated that, <italic>S. globosa</italic>, <italic>S. schenckii</italic>, and <italic>S. brasiliensis</italic> were the most identified species. With respect to the deposit and maintenance of species, we observed that only 17% of the strains of <italic>Sporothrix</italic> sp. isolated in the world are preserved in a culture collection.</p></sec><sec><title>Conclusions</title><p>This systematic review confirmed a difficulty in obtaining the frequency of <italic>Sporothrix</italic> species stored in culture collection and insufficient data on the molecular identification mainly of animal sporotrichosis and isolation of <italic>Sporothrix</italic> sp. in environmental samples.</p></sec>