AUTHOR=Zhang Yingmiao , Fan Yue , Zhan Yu , Wang Hao , Li Xun , Wang Hui , Feng Tian , Shi Lifeng , Wang Jing , Wang Hui , Lu Zhongxin 

TITLE=Genomic characterization of Pantoea anthophila strain UI705 causing urinary tract infections in China

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=13

YEAR=2023

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2023.1208473

DOI=10.3389/fcimb.2023.1208473

ISSN=2235-2988

ABSTRACT=<sec><title>Introduction</title><p><italic>Pantoea anthophila</italic> (<italic>P. anthophila</italic>) is a Gram-negative bacterium initially isolated from <italic>Impatiens balsamina</italic> in India. <italic>P. anthophila</italic> has been characterized with low pathogenicity, and no human infections caused by this organism have been reported yet. We report the first case of urinary tract infection caused by <italic>P. anthophila</italic> in a 73-year-old man after bladder cancer surgery.</p></sec><sec><title>Methods</title><p>The bacterial isolate gained from urine was named UI705 and identified as <italic>P. anthophila</italic> by MALDI-TOF mass spectrometry. The genome sequencing and analysis were performed to further characterize the pathogenesis of the clinical isolate.</p></sec><sec><title>Result and discussion</title><p>To the best of our knowledge, this is the first report of human infection caused by <italic>P. anthophila</italic> in China. The draft genome sequence of <italic>P. anthophila</italic> UI705 provides a fundamental resource for subsequent investigation of its virulence factors, antibiotic resistance, host–pathogen interactions, and comparative genomics of genus <italic>Pantoea</italic>.</p></sec>