AUTHOR=Li Jialin , Liu Lesen , Zhang Hua , Guo Jing , Wei Xiaoling , Xue Min , Ma Xiang 

TITLE=Severe problem of macrolides resistance to common pathogens in China

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=13

YEAR=2023

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2023.1181633

DOI=10.3389/fcimb.2023.1181633

ISSN=2235-2988

ABSTRACT=<p>With the widespread use of macrolide antibiotics in China, common pathogens causing children’s infections, such as <italic>Streptococcus pneumoniae</italic>, <italic>Streptococcus</italic> (including <italic>Group A streptococcus</italic>, <italic>Group B streptococcus</italic>), <italic>Staphylococcus aureus</italic>, <italic>Bordetella pertussis</italic>, and <italic>Mycoplasma pneumoniae</italic>, have shown varying degrees of drug resistance. In order to provide such problem and related evidence for rational use of antibiotics in clinic, we reviewed the drug resistance of common bacteria to macrolides in children recent 20 years.</p>