Previous studies have indicated that nitric oxide synthase 2 (
Altogether 704 participants, including 336 PTOM patients and 368 healthy controls, were genotyped of rs2297514 and rs2248814 of the
Outcomes showed that the frequency of allele C of rs2297514 in the patient group was significantly lower than that in the control group (48.7%
In this Chinese cohort, rs2297514 is correlated with a decreased risk of PTOM development, with genotype CC as a protective factor.