AUTHOR=Personnic Nicolas , Doublet Patricia , Jarraud Sophie TITLE=Intracellular persister: A stealth agent recalcitrant to antibiotics JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=13 YEAR=2023 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2023.1141868 DOI=10.3389/fcimb.2023.1141868 ISSN=2235-2988 ABSTRACT=

The bulk of bacteria transiently evading appropriate antibiotic regimes and recovered from non-resolutive infections are commonly refer to as persisters. In this mini-review, we discuss how antibiotic persisters stem from the interplay between the pathogen and the cellular defenses mechanisms and its underlying heterogeneity.