AUTHOR=Song Chang , Li Zesong , Li Chen , Huang Meiying , Liu Jianhong , Fang Qiuping , Cao Zitong , Zhang Lin , Gao Pengbo , Nie Wendi , Luo Xueyao , Kang Jianhao , Xie Shimin , Lyu Jianxin , Zhu Xiao TITLE=SARS-CoV-2: The Monster Causes COVID-19 JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=12 YEAR=2022 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2022.835750 DOI=10.3389/fcimb.2022.835750 ISSN=2235-2988 ABSTRACT=

Coronaviruses are viruses whose particles look like crowns. SARS-CoV-2 is the seventh member of the human coronavirus family to cause COVID-19 which is regarded as a once-in-a-century pandemic worldwide. It holds has the characteristics of a pandemic, which has broy -55ught many serious negative impacts to human beings. It may take time for humans to fight the pandemic. In addition to humans, SARS-CoV-2 also infects animals such as cats. This review introduces the origins, structures, pathogenic mechanisms, characteristics of transmission, detection and diagnosis, evolution and variation of SARS-CoV-2. We summarized the clinical characteristics, the strategies for treatment and prevention of COVID-19, and analyzed the problems and challenges we face.