AUTHOR=Li Xinquan , Wang Qiang , Hu Xiafen , Liu Wanxin 

TITLE=Current Status of Probiotics as Supplements in the Prevention and Treatment of Infectious Diseases

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=12

YEAR=2022

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2022.789063

DOI=10.3389/fcimb.2022.789063

ISSN=2235-2988

ABSTRACT=<p>Probiotics play an important role against infectious pathogens <italic>via</italic> their effects on the epithelium, the production of antimicrobial compounds, and competitive exclusion. Administration of probiotic supplements may reduce the risk of infectious diseases and the use of antibiotics, hence contributing to a reduction or a delay of the development of multi-resistant bacteria. Infection is a constant concern for people who experience recurrent infections, and antibiotic treatment usually fails due to antibiotic resistance. Therefore, an infection can lead to severe illness and hospitalization if left untreated. A growing number of studies have demonstrated promising results for a variety of probiotic strains used to prevent or treat acute and recurrent infectious diseases, but additional standardized clinical research is needed.</p>