AUTHOR=Leseigneur Clarisse , Lê-Bury Pierre , Pizarro-Cerdá Javier , Dussurget Olivier TITLE=Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2020.577559 DOI=10.3389/fcimb.2020.577559 ISSN=2235-2988 ABSTRACT=

Macrophages participate to the first line of defense against infectious agents. Microbial pathogens evolved sophisticated mechanisms to escape macrophage killing. Here, we review recent discoveries and emerging concepts on bacterial molecular strategies to subvert macrophage immune responses. We focus on the expanding number of fascinating subversive tools developed by Listeria monocytogenes, Staphylococcus aureus, and pathogenic Yersinia spp., illustrating diversity and commonality in mechanisms used by microorganisms with different pathogenic lifestyles.