AUTHOR=Freire-Paspuel Byron , Vega-MariƱo Patricio , Velez Alberto , Castillo Paulina , Gomez-Santos Eliana Elizabeth , Cruz Marilyn , Garcia-Bereguiain Miguel Angel TITLE=Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=10 YEAR=2020 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2020.00356 DOI=10.3389/fcimb.2020.00356 ISSN=2235-2988 ABSTRACT=

CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries.