AUTHOR=Younes Salma , Al-Sulaiti Asma , Nasser Elham Abdulwahab Ahmed , Najjar Hoda , Kamareddine Layla 

TITLE=Drosophila as a Model Organism in Host–Pathogen Interaction Studies

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=10

YEAR=2020

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2020.00214

DOI=10.3389/fcimb.2020.00214

ISSN=2235-2988

ABSTRACT=<p>Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the <italic>Drosophila</italic> model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in <italic>Drosophila</italic> serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.</p>