AUTHOR=Pflughoeft Kathryn J. , Mash Michael , Hasenkampf Nicole R. , Jacobs Mary B. , Tardo Amanda C. , Magee D. Mitchell , Song Lusheng , LaBaer Joshua , Philipp Mario T. , Embers Monica E. , AuCoin David P. TITLE=Multi-platform Approach for Microbial Biomarker Identification Using Borrelia burgdorferi as a Model JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=9 YEAR=2019 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2019.00179 DOI=10.3389/fcimb.2019.00179 ISSN=2235-2988 ABSTRACT=
The identification of microbial biomarkers is critical for the diagnosis of a disease early during infection. However, the identification of reliable biomarkers is often hampered by a low concentration of microbes or biomarkers within host fluids or tissues. We have outlined a multi-platform strategy to assess microbial biomarkers that can be consistently detected in host samples, using