AUTHOR=Yang Ruifu , Du Zongmin , Han Yanping , Zhou Lei , Song Yajun , Zhou Dongsheng , Cui Yujun 

TITLE=Omics strategies for revealing Yersinia pestis virulence

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=2

YEAR=2012

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2012.00157

DOI=10.3389/fcimb.2012.00157

ISSN=2235-2988

ABSTRACT=<p>Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach. Mass datasets produced from omics-based studies require experts from different fields to reveal the salient features behind these data. In this review, we summarize omics-driven studies to reveal the virulence features of <italic>Yersinia pestis</italic> through genomics, trascriptomics, proteomics, interactomics, etc. These studies serve as foundations for further hypothesis-driven research and help us gain insight into <italic>Y. pestis</italic> pathogenesis.</p>