AUTHOR=Swords W E.

TITLE=Quorum signaling and sensing by nontypeable Haemophilus influenzae

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=2

YEAR=2012

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2012.00100

DOI=10.3389/fcimb.2012.00100

ISSN=2235-2988

ABSTRACT=<p>Quorum signals are diffusible factors produced by bacteria that coordinate communal responses. For nontypeable <italic>Haemophilus influenzae</italic> (NT<italic>Hi</italic>), a series of recent papers indicate that production and sensing of quorum signals are determinants of biofilm formation/maturation and persistence <italic>in vivo</italic>. In this mini-review I will summarize the current knowledge about quorum signaling/sensing by this organism, and identify specific topics for additional study.</p>