Frontiers in Cell and Developmental Biology

Brief Research Report

Published on 30 Apr 2025

Using a brain-like endothelial cell differentiation to characterize the CS79iBRCA-n2 BRCA1 mutated patient derived stem cell line

Natalie G. Alexander
Kylie A. Buchanan
Alexandra E. Meyer
Lauren M. Mitterway
Caroline O. Vanderburgh
Shreyas S. Rao
Brandon J. Kim

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1516669

178 views

Review

Published on 30 Apr 2025

Oxidative cell death in the central nervous system: mechanisms and therapeutic strategies

Nan Liu
Ya Liu
Yingzhao Wang
Chunsheng Feng
Meihua Piao
Ming Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1562344

Review

Published on 30 Apr 2025

Challenges of in vitro modelling of liver fibrosis

Patricia Ros-Tarraga
Estela Villanueva-Badenas
Estela Sanchez-Gonzalez
Gloria Gallego-Ferrer
M. Teresa Donato
Laia Tolosa

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1567916

Original Research

Published on 30 Apr 2025

A phylogenetic analysis of the CDKL protein family unravels its evolutionary history and supports the Drosophila model of CDKL5 deficiency disorder

María del Carmen Martín-Carrascosa
Christian Palacios-Martínez
Máximo Ibo Galindo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582684

182 views

Review

Published on 30 Apr 2025

Caspase-mediated pathways in retinal ganglion cell injury: a novel therapeutic target for glaucoma

Nisha Rajakrishna
Seok Ting Lim
Xiaomeng Wang
Tina T. Wong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1586240

132 views

Review

Accepted on 29 Apr 2025

"Proteinjury": a Universal Pathological Mechanism Mediated by Cerebrospinal Fluid in Neurodegeneration and Trauma

Vladimir F Lazarev
Bashar A Alhasan
Irina V Guzhova
Boris A Margulis

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593122

Original Research

Accepted on 29 Apr 2025

Optimizing single cell RNA sequencing of stem cells. A streamlined workflow for enhanced sensitivity and reproducibility in hematopoietic studies. The use of human umbilical cord blood-derived hematopoietic stem and progenitor cells

Justyna Jarczak
Patrycja Kieszek
Mariusz Z Ratajczak
Magdalena Kucia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1590889

Original Research

Accepted on 29 Apr 2025

Immunolocalization and proteomic analyses of IZUMO1 in porcine spermatozoa

Miranda Hernández-Falcó
Paula Sáez-Espinosa
Andrea López-Botella
Laura Robles-Gómez
Francisco Garcia Vazquez
Maria José IZQUIERDO RICO
Pedro José Llamas-López
María José Gómez-Torres

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1576881

Review

Accepted on 29 Apr 2025

Architecture and Molecular Machinery of Skeletal Myofibers: A Systematic Review of Structure-Function Relationships

Jing Zhao
Xu Du
Wei Fang
Hongxia Zhu
Binglin Yue

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1602607

Mini Review

Accepted on 29 Apr 2025

Mechanisms of the FLASH Effect: Current Insights and Advances

Giulia Rosini
Esther Ciarrocchi
Beatrice D'Orsi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1575678

Original Research

Published on 29 Apr 2025

Systematic optimization of prime editing for enhanced efficiency and versatility in genome engineering across diverse cell types

Huiling Mu
Yeyi Liu
Yijia Chi
Fei Wang
Shuting Meng
Yi Zhang
Xunting Wang
Dongxin Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1589034

493 views

Original Research

Published on 29 Apr 2025

Omic AI reveals new autophagy regulators from the Atg1 interactome in Saccharomyces cerevisiae

Cheng Han
Shanshan Fu
Dachao Tang
Yuting Chen
Dan Liu
Zihao Feng
Yujie Gou
Chi Zhang
Weizhi Zhang
Leming Xiao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1554958

248 views

Original Research

Published on 29 Apr 2025

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

Cécile Méjécase
Ya Zhou
Nicholas Owen
Pablo Soro-Barrio
Riccardo Cheloni
Neelima Nair
Hajrah Sarkar
Lyes Toualbi
Mariya Moosajee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1511066

419 views

Original Research

Published on 29 Apr 2025

Mitochondria-derived reactive oxygen species induce over-differentiation of neural stem/progenitor cells after non-cytotoxic cisplatin exposure

Felipe A. Bustamante-Barrientos
Eliana Lara-Barba
Yeimi Herrera-Luna
Cynthia García-Guerrero
Eduardo Silva-Pavez
Jonathan Morales-Reyes
María Jesús Araya
Liliana Yanten-Fuentes
Noymar Luque-Campos
Claudia Altamirano

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1555153

377 views

Mini Review

Published on 29 Apr 2025

Rethinking MYC inhibition: a multi-dimensional approach to overcome cancer’s master regulator

Jing Yu
Dan Liu
Yujian Yuan
Chunxia Sun
Zihan Su

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1601975

159 views

Original Research

Accepted on 28 Apr 2025

Identifying a prognostic signature for clear cell renal cell carcinoma: the convergence of single-cell and bulk sequencing with machine learning

Yude Hong
Xiao Hu
Zhuolun Sun
Libo Chen
Mingyong Li
Mingxiao Zhang
Weiming Deng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1560095