AUTHOR=Liu Junzhe , Li Fengze , Cao Yulong , Lv Yonghui , Lei Kunjian , Tu Zewei , Gong Chuandong , Wang Haiyan , Liu Feng , Huang Kai TITLE=Mechanisms underlining R-loop biology and implications for human disease JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=13 YEAR=2025 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2025.1537731 DOI=10.3389/fcell.2025.1537731 ISSN=2296-634X