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REVIEW article

Front. Cell Dev. Biol.
Sec. Membrane Traffic and Organelle Dynamics
Volume 12 - 2024 | doi: 10.3389/fcell.2024.1490870
This article is part of the Research Topic Role of Lipids in Membrane Trafficking: Future Challenges View all 4 articles

Sorting of the complex sphingolipids within the cellular endomembrane systems

Provisionally accepted
Victor O Svistunov Victor O Svistunov 1Kigumbi J Ehrmann Kigumbi J Ehrmann 1Wayne I Lencer Wayne I Lencer 2Stefanie S Schmieder Stefanie S Schmieder 2*
  • 1 Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, United States
  • 2 Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States

The final, formatted version of the article will be published soon.

    Cells contain a plethora of structurally different diverse lipid species, which are unevenly distributed across the different cellular membrane compartments. Some of these lipid species require vesicular trafficking to reach their subcellular destinations. Here, we review recent advances made in the field that contribute to understanding lipid sorting during endomembrane trafficking.

    Keywords: membrane nanodomains, Endocytosis, Membrane trafficking, membrane curvature, membrane rafts, complex sphingolipids

    Received: 03 Sep 2024; Accepted: 25 Nov 2024.

    Copyright: © 2024 Svistunov, Ehrmann, Lencer and Schmieder. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Stefanie S Schmieder, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, 02115, Massachusetts, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.