Yifei Li
1*
Jingxian Shi
1
Yuxi Jin
1
Lin Sha
1
Li Xing
1
Donghui Zhang
2
Jinlin Wu
1*
Yan Qi
2*The final, formatted version of the article will be published soon.
REVIEW article
Front. Cell Dev. Biol.
Sec. Cellular Biochemistry
Volume 12 - 2024 |
doi: 10.3389/fcell.2024.1475603
This article is part of the Research Topic Pathogenesis Insights and Innovative Strategies: Exploring Atherosclerosis and Cardiovascular Diseases View all articles
Mitochondrial Non-energetic Function and Embryonic Cardiac Development
Provisionally accepted- 1 West China Second University Hospital, Sichuan University, Chengdu, China
- 2 Hubei University, Wuhan, Hubei Province, China
The initial contraction of the heart during the embryonic stage necessitates a substantial energy supply, predominantly derived from mitochondrial function. However, during embryonic heart development, mitochondria influence beyond energy supplementation. Increasing evidence suggests that mitochondrial permeability transition pore opening and closing, mitochondrial fusion and fission, mitophagy, reactive oxygen species production, apoptosis regulation, Ca 2+ homeostasis, and cellular redox state also play critical roles in early cardiac development. Therefore, this review aims to describe the essential roles of mitochondrial non-energetic function embryonic cardiac development.
Keywords: Mitochondria, cardiac development, embryo, non-energetic function, ROS Font: Not Bold, Complex Script Font: Not Bold
Received: 04 Aug 2024; Accepted: 20 Sep 2024.
Copyright: © 2024 Li, Shi, Jin, Sha, Xing, Zhang, Wu and Qi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yifei Li, West China Second University Hospital, Sichuan University, Chengdu, China
Jinlin Wu, West China Second University Hospital, Sichuan University, Chengdu, China
Yan Qi, Hubei University, Wuhan, 430062, Hubei Province, China
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