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REVIEW article

Front. Cell Dev. Biol.
Sec. Stem Cell Research
Volume 12 - 2024 | doi: 10.3389/fcell.2024.1440091
This article is part of the Research Topic Current Methods for Detecting and Diagnosing Stem Cell Pathogenesis: A Focus on Translational Interventions in the Contemporary Disease and Technology Landscape View all articles

In Vitro Detection of Marine Invertebrate Stem Cells: Utilizing Molecular and Cellular Biology Techniques and Exploring Markers

Provisionally accepted
Fatemeh Mohajer Fatemeh Mohajer 1,2,3Arezoo Khoradmehr Arezoo Khoradmehr 1,2Tuba Zendehboudi Tuba Zendehboudi 1,2,3Behnaz Riazalhosseini Behnaz Riazalhosseini 1,2,4Iraj Nabipour Iraj Nabipour 1,2Neda Baghban Neda Baghban 1,2*
  • 1 The Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, Bushehr, Iran
  • 2 Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Bushehr, Iran
  • 3 Student Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, Iran
  • 4 The Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

The final, formatted version of the article will be published soon.

    Marine invertebrate stem cells (MISCs) represent a distinct category of pluripotent and totipotent cells with remarkable abilities for self-renewal and differentiation into multiple germ layers, akin to their vertebrate counterparts. These unique cells persist throughout an organism's adult life and have been observed in various adult marine invertebrate phyla. MISCs play crucial roles in numerous biological processes, including developmental biology phenomena specific to marine invertebrates, such as senescence, delayed senescence, whole-body regeneration, and asexual reproduction. Furthermore, they serve as valuable models for studying stem cell biology. Despite their significance, information about MISCs remains scarce and scattered in the scientific literature. In this review, we have carefully collected and summarized valuable information about MISC detection by perusing the articles that study and detect MISCs in various marine invertebrate organisms. The review begins by defining MISCs and highlighting their unique features compared to vertebrates. It then discusses the common markers for MISC detection and in vitro techniques employed in invertebrate and vertebrates investigation. This comprehensive review provides researchers and scientists with a cohesive and succinct overview of MISC characteristics, detection methods, and associated biological phenomena in marine invertebrate organisms. We aim to offer a valuable resource to researchers and scientists interested in marine invertebrate stem cells, fostering a better understanding of their broader implications in biology. With ongoing advancements in scientific techniques and the continued exploration of marine invertebrate species, we anticipate that further discoveries will expand our knowledge of MISCs and their broader implications in biology.

    Keywords: Invertebrates, Stem Cells, marker, marine, Regeneration, Reproduction

    Received: 28 May 2024; Accepted: 07 Aug 2024.

    Copyright: © 2024 Mohajer, Khoradmehr, Zendehboudi, Riazalhosseini, Nabipour and Baghban. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Neda Baghban, The Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, Bushehr, Iran

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.