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REVIEW article

Front. Cell Dev. Biol.
Sec. Cancer Cell Biology
Volume 12 - 2024 | doi: 10.3389/fcell.2024.1427724
This article is part of the Research Topic The Molecular Mechanisms of Circulating Biomarkers in Lung Cancer View all articles

miR-137: a potential therapeutic target for lung cancer

Provisionally accepted
Shuanshuan Liu Shuanshuan Liu *Yanyun Ruan Yanyun Ruan *Xu Chen Xu Chen *Bao He Bao He *Qi Chen Qi Chen *
  • Taizhou Central Hospital, Taizhou, China

The final, formatted version of the article will be published soon.

    Lung cancer is a prevalent malignancy and the leading cause of cancerrelated deaths, posing a significant threat to human health. Despite advancements in treatment, the prognosis for lung cancer patients remains poor due to late diagnosis, cancer recurrence, and drug resistance. Epigenetic research, particularly in microRNAs, has introduced a new avenue for cancer prevention and treatment. MicroRNAs, including miR-137, play a vital role in tumor development by regulating various cellular processes. MiR-137 has garnered attention for its tumor-suppressive properties, with studies showing its potential in inhibiting cancer progression. In lung cancer, miR-137 is of particular interest, with numerous reports exploring its role and mechanisms.A comprehensive review is necessary to consolidate current evidence. This review highlights recent studies on miR-137 in lung cancer, covering cell proliferation, migration, apoptosis, drug resistance, and therapy, emphasizing its potential as a biomarker and therapeutic target for lung cancer treatment and prognosis.

    Keywords: miR-137, lung cancer, Therapeutic target, biomarker, MicroRNAs

    Received: 04 May 2024; Accepted: 08 Aug 2024.

    Copyright: © 2024 Liu, Ruan, Chen, He and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Shuanshuan Liu, Taizhou Central Hospital, Taizhou, China
    Yanyun Ruan, Taizhou Central Hospital, Taizhou, China
    Xu Chen, Taizhou Central Hospital, Taizhou, China
    Bao He, Taizhou Central Hospital, Taizhou, China
    Qi Chen, Taizhou Central Hospital, Taizhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.