AUTHOR=Zhang Chencheng , Liu Jibin , Wu Jun , Ranjan Kamakshi , Cui Xiaopeng , Wang Xingdan , Zhang Dianzheng , Zhu Shudong TITLE=Key molecular DNA damage responses of human cells to radiation JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2024.1422520 DOI=10.3389/fcell.2024.1422520 ISSN=2296-634X ABSTRACT=

Our understanding of the DNA damage responses of human cells to radiation has increased remarkably over the recent years although some notable signaling events remain to be discovered. Here we provide a brief account of the key molecular events of the responses to reflect the current understanding of the key underlying mechanisms involved.