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ORIGINAL RESEARCH article

Front. Cell Dev. Biol.
Sec. Molecular and Cellular Pathology
Volume 12 - 2024 | doi: 10.3389/fcell.2024.1415788
This article is part of the Research Topic Glycocalyx in Physiology and Vascular Related Diseases – Volume II View all 8 articles

Serum syndecan-1 as an independent predictor of high-risk vulnerable plaque in atherosclerotic mice

Provisionally accepted
Yan Qiu Yan Qiu 1,2OUYANG ZHI OUYANG ZHI 1Jian Zhong Jian Zhong 1Linlu Jin Linlu Jin 1Yixue Qin Yixue Qin 1Ye Zeng Ye Zeng 1*
  • 1 Sichuan University, Chengdu, China
  • 2 Yunnan Fuwai Cardiovascular Hospital, Kunming, Yunnan Province, China

The final, formatted version of the article will be published soon.

    This study highlights the significance of syndecan-1 in plaque vulnerability and provides valuable insights into the formation of high-risk vulnerable plaques in atherosclerosis. These findings have substantial implications for cardiovascular disease management, as early identification of vulnerable plaques can lead to timely interventions and prevent life-threatening events. Moreover, the exploration of syndecan-1 as a biomarker offers a promising tool for risk stratification and personalized treatment approaches.

    Keywords: Atherosclerosis, Vulnerable Plaque, Glycocalyx, Syndecan-1, Sphingosine

    Received: 26 Apr 2024; Accepted: 25 Jul 2024.

    Copyright: © 2024 Qiu, ZHI, Zhong, Jin, Qin and Zeng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ye Zeng, Sichuan University, Chengdu, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.