AUTHOR=Que Hanyun , Mai Erziya , Hu Yanting , Li Hong , Zheng Wenxin , Jiang Yuchen , Han Feiruo , Li Xuedong , Gong Puyang , Gu Jian TITLE=Multilineage-differentiating stress-enduring cells: a powerful tool for tissue damage repair JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2024.1380785 DOI=10.3389/fcell.2024.1380785 ISSN=2296-634X ABSTRACT=
Multilineage-differentiating stress-enduring (Muse) cells are a type of pluripotent cell with unique characteristics such as non-tumorigenic and pluripotent differentiation ability. After homing, Muse cells spontaneously differentiate into tissue component cells and supplement damaged/lost cells to participate in tissue repair. Importantly, Muse cells can survive in injured tissue for an extended period, stabilizing and promoting tissue repair. In addition, it has been confirmed that injection of exogenous Muse cells exerts anti-inflammatory, anti-apoptosis, anti-fibrosis, immunomodulatory, and paracrine protective effects