This article is a correction to:
Adiponectin Modified BMSCs Alleviate Heart Fibrosis via Inhibition TGF-beta1/Smad in Diabetic Rats
Ke Meng1,2†
Simin Cai
Xiaoming Zhang- 1Department of Anatomy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China
- 2Department of Emergency Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China
A Corrigendum on
Adiponectin modified BMSCs alleviate heart fibrosis via inhibition TGF-beta1/smad in diabetic rats
by Meng K, Cai H, Cai S, Hong Y and Zhang X (2021). Front. Cell Dev. Biol. 9:644160. doi: 10.3389/fcell.2021.644160
In the published article, there was an error in Figures 4–6 as published. The tissue photograph of Figure 4A DM + BMSC + APN+, Figure 5A DM + BMSC + APN-, Figure 5B collagen I DM + BMSC &DM + BMSC + APN-, Figure 6A DM + BMSC + APN- are wrong. The corrected Figures 4–6 appear below.
FIGURE 4
FIGURE 4. APN attenuated pathological changes in the hearts of diabetic rats. (A) Representative micrographs of myocardial tissue sections stained with hematoxylin and eosin (scale bar: 50 µm) (B) Quantitative analysis of myocyte size area. Data are mean ± SD; *p < 0.05, **p < 0.01.
FIGURE 5
FIGURE 5. Effect of APN on collagen deposition. (A) Representative Masson’s trichrome staining (B) Immunostaining of collagen I and collagen III. (C) Quantitative analysis of Masson’s trichrome staining. (D) Immunohistochemistry analysis of collagens I. (E) Immunohistochemistry analysis of collagens III. Data are mean ± SD; *p < 0.05, **p < 0.01.
FIGURE 6
FIGURE 6. The expression of TGF-β1/Smad 2,3 in all groups rats. (A) Immunostaining of TGF-β1, Smad2 and Smad3. (B) Quantitative analysis of TGF-β1. (C) Quantitative analysis of Smad2. (D) Quantitative analysis of Smad3. (E) Representative Western blot: TGF-β1, Smad2, P-smad2, Smad3, and P-smad3. (F) The Western blot assay of TGF-β1. (G) The Western blot assay of Smad2. (H) The Western blot assay of P-smad2. (I) The Western blot assay of Smad3. (J) The Western blot assay of P-smad3. Data are mean ± SD; *p < 0.05, **p < 0.01.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: diabetic cardiomyopathy, adiponectin, bone marrow mesenchymal stem cells, TGF-beta1, myocardial fibrosis
Citation: Meng K, Cai H, Cai S, Hong Y and Zhang X (2023) Corrigendum: Adiponectin modified BMSCs alleviate heart fibrosis via inhibition TGF-beta1/smad in diabetic rats. Front. Cell Dev. Biol. 11:997572. doi: 10.3389/fcell.2023.997572
Received: 19 July 2022; Accepted: 27 April 2023;
Published: 11 May 2023.
Edited and Reviewed by:
Lei Ye, National Heart Centre Singapore, SingaporeCopyright © 2023 Meng, Cai, Cai, Hong and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Yucai Hong, zrhyc@hotmail.com; Xiaoming Zhang, zxm@zju.edu.cn
†These authors have contributed equally to this work