This article is a correction to:
METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification
Xinying Zhou
Yang Yang1
Dawei Kang- 1Department of Spine Surgery, Center for Orthopaedic Surgery, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China
- 2Department of Orthopedics, Longtan Hospital of Guangxi Autonomous Region, Liuzhou, China
A Corrigendum on
METTL3 contributes to osteosarcoma progression by increasing DANCR mRNA stability via m6A modification
by Zhou X, Yang Y, Li Y, Liang G, Kang D, Zhou B and Li Q (2022) Front. Cell Dev. Biol. 9:784719. doi: 10.3389/fcell.2021.784719
In the published article, there was an error in Figure 4 as published. The corrected Figure 4 and its caption appear below.
FIGURE 4
FIGURE 4. The METTL3/lncRNA DANCR axis promotes OS cell tumorigenesis and progression. (A) Correlations between METTL3 and DANCR expression in OS tissue (n = 40). (B) RT-qPCR showing increased DANCR levels in OS tumor tissues when compared with matched normal tissues. (C) Kaplan–Meier survival analyses of patients with OS. Patients with higher DANCR levels showed a relatively poor prognosis. (D) RT-qPCR showing elevated DANCR expression in Saos-2, SJSA-1, MG63, HOS, and U-2 OS cells compared with human fetal osteoblastic cells. CCK-8 assays were used to determine viability in HOS (E) and U-2 OS (F) cells transfected with si-DANCR or the corresponding control. Transwell assays were used to assess the migration activities of HOS and U-2 OS cells. (G) Quantitative analyses of migrating cells passing through membranes without Matrigel. (H) Representative images of OS cell migration. Transwell assays were used to examine the invasion activities of HOS and U-2 OS cells. (I) Quantitative analyses of migrating cells passing through membranes plus Matrigel. (J) Representative images of OS cell invasion. (K, L) Relative METTL3 expression with or without si-DANCR infected. *p < 0.05.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: osteosarcoma, m6A modification, METTL3, lncRNA DANCR, mRNA stability
Citation: Zhou X, Yang Y, Li Y, Liang G, Kang D, Zhou B and Li Q (2023) Corrigendum: METTL3 contributes to osteosarcoma progression by increasing DANCR mRNA stability via m6A modification. Front. Cell Dev. Biol. 11:1167476. doi: 10.3389/fcell.2023.1167476
Received: 16 February 2023; Accepted: 16 June 2023;
Published: 03 July 2023.
Edited and reviewed by:
Birija Sankar Patro, Bhabha Atomic Research Centre (BARC), IndiaCopyright © 2023 Zhou, Yang, Li, Liang, Kang, Zhou and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Bing Zhou, NzQ3MjM4NzA5QHFxLmNvbQ==; Qingchu Li, bHFjMTZAMjYzLm5ldA==