AUTHOR=Ding Meng , Li Hongyu , Zheng Lan 

TITLE=Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

JOURNAL=Frontiers in Cell and Developmental Biology

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.966531

DOI=10.3389/fcell.2022.966531

ISSN=2296-634X

ABSTRACT=<p>Exercise is one of the most effective treatments for the diseases of aging. In recent years, a growing number of researchers have used <italic>Drosophila</italic> melanogaster to study the broad benefits of regular exercise in aging individuals. With the widespread use of <italic>Drosophila</italic> exercise models and the upgrading of the <italic>Drosophila</italic> exercise apparatus, we should carefully examine the differential contribution of regular exercise in the aging process to facilitate more detailed quantitative measurements and assessment of the exercise phenotype. In this paper, we review some of the resources available for <italic>Drosophila</italic> exercise models. The focus is on the impact of regular exercise or exercise adaptation in the aging process in <italic>Drosophila</italic> and highlights the great potential and current challenges faced by this model in the field of anti-aging research.</p>