AUTHOR=Torii Tomohiro , Miyasaka Tomohiro , Misonou Hiroaki 

TITLE=The organization of microtubules and Tau in oligodendrocytes: Tau pathology in damaged oligodendrocytes

JOURNAL=Frontiers in Cell and Developmental Biology

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.950682

DOI=10.3389/fcell.2022.950682

ISSN=2296-634X

ABSTRACT=<p>Tau is abundantly expressed in neurons, however previous reports and our recent study showed tau also exist in oligodendrocytes. Also the expression levels of tau are dramatical changed in hypomyelination model rat and in demyelination region of stroke model mice. The review demonstrate microtubule and its binding partner Tau might be necessary for oligodendrocyte function based on previous reports.</p>