AUTHOR=An Zhenyi , Chiang Wei-Chung , Fernández Álvaro F. , Franco Luis H. , He CongCong , Huang Shu-Yi , Lee Eunmyong , Liu Yang , Sebti Salwa , Shoji-Kawata Sanae , Sirasanagandla Shyam , Wang Richard C. , Wei Yongjie , Zhao Yuting , Vega-Rubin-de-Celis Silvia TITLE=Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.891332 DOI=10.3389/fcell.2022.891332 ISSN=2296-634X ABSTRACT=

With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.