SNORA72 Activates the Notch1/c-Myc Pathway to Promote Stemness Transformation of Ovarian Cancer Cells
- 1Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China
- 2Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation, China Medical University, Shenyang, China
- 3Liaoning Cancer Immune Peptide Drug Engineering Technology Research Center, China Medical University, Shenyang, China
- 4Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, China Medical University, Shenyang, China
A Corrigendum on
SNORA72 activates the Notch1/c-Myc pathway to promote stemness transformation of ovarian cancer cells
by Zhang L, Ma R, Gao M, Zhao Y, Lv X, Zhu W, Han L, Su P, Fan Y, Yan Y, Zhao L, Ma H, Wei M and He M (2020). Front. Cell Dev. Biol. 8:583087. doi: 10.3389/fcell.2020.583087
In the original article, there was a mistake in Figure 1 as published. The transwell picture for CA in Figure 1C was mistaken and misused. The corrected Figure 1 appears below.
FIGURE 1. SNORA72 is overexpressed in ovarian cancer stems cells (OCSCs). (A) Morphology of OVCAR-3 (OV), OVCAR-3 spheroid (OS), CAOV-3 (CA), and CAOV-3 spheroid (CS) cells shown under a microscope (×10). (B) Expression of CD133 detected by flow cytometry in OV vs. OS and in CA vs. CS cells. (C) Migration abilities of OV, OS, CA, and CS cells by Transwell assay. (D) Differentiation morphology of OS and CS cells at 0, 12, 24, 48, and 72 h. (E) Hierarchical clustering analysis of small nucleolar RNA (snoRNA) expression from non-coding RNA-ChIP data in OV and OS cells. Red, higher expression levels; green, lower expression levels. (F) Relative SNORA72 expression to U6, as an endogenous control, analyzed by qRT-PCR in OV and OS cells. The SNORA72 expression in OV cells was set as 1. Data are shown as the mean ± SD from three independent experiments. **p < 0.01, ****p < 0.0001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: SNORA72, ovarian cancer stem cells (OCSCs), Notch1, c-Myc, stemness
Citation: Zhang L, Ma R, Gao M, Zhao Y, Lv X, Zhu W, Han L, Su P, Fan Y, Yan Y, Zhao L, Ma H, Wei M and He M (2022) Corrigendum: SNORA72 activates the Notch1/c-Myc pathway to promote stemness transformation of ovarian cancer cells. Front. Cell Dev. Biol. 10:819798. doi: 10.3389/fcell.2022.819798
Received: 22 November 2021; Accepted: 29 July 2022;
Published: 26 August 2022.
Edited and reviewed by:
Atsushi Asakura, University of Minnesota Twin Cities, United StatesCopyright © 2022 Zhang, Ma, Gao, Zhao, Lv, Zhu, Han, Su, Fan, Yan, Zhao, Ma, Wei and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Miao He, hemiao_cmu@126.com; Minjie Wei, weiminjiecmu@163.com
†These authors have contributed equally to this work