AUTHOR=Harreguy Maria B , Tanvir Zainab , Shah Esha , Simprevil Blandine , Tran Tracy S , Haspel Gal TITLE=Semaphorin signaling restricts neuronal regeneration in C. elegans JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.814160 DOI=10.3389/fcell.2022.814160 ISSN=2296-634X ABSTRACT=
Extracellular signaling proteins serve as neuronal growth cone guidance molecules during development and are well positioned to be involved in neuronal regeneration and recovery from injury. Semaphorins and their receptors, the plexins, are a family of conserved proteins involved in development that, in the nervous system, are axonal guidance cues mediating axon pathfinding and synapse formation. The