AUTHOR=Singh Narendra Pratap , Krumlauf Robb TITLE=Diversification and Functional Evolution of HOX Proteins JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.798812 DOI=10.3389/fcell.2022.798812 ISSN=2296-634X ABSTRACT=
Gene duplication and divergence is a major contributor to the generation of morphological diversity and the emergence of novel features in vertebrates during evolution. The availability of sequenced genomes has facilitated our understanding of the evolution of genes and regulatory elements. However, progress in understanding conservation and divergence in the function of proteins has been slow and mainly assessed by comparing protein sequences in combination with