AUTHOR=Mahanty Sarmistha , Setty Subba Rao Gangi TITLE=Epidermal Lamellar Body Biogenesis: Insight Into the Roles of Golgi and Lysosomes JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=9 YEAR=2021 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.701950 DOI=10.3389/fcell.2021.701950 ISSN=2296-634X ABSTRACT=
Epidermal lamellar bodies (eLBs) are secretory organelles that carry a wide variety of secretory cargo required for skin homeostasis. eLBs belong to the class of lysosome-related organelles (LROs), which are cell-type-specific organelles that perform diverse functions. The formation of eLBs is thought to be related to that of other LROs, which are formed either through the gradual maturation of Golgi/endosomal precursors or by the conversion of conventional lysosomes. Current evidence suggests that eLB biogenesis presumably initiate from