AUTHOR=Laulajainen-Hongisto Anu , Toppila-Salmi Sanna Katriina , Luukkainen Annika , Kern Robert 

TITLE=Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases

JOURNAL=Frontiers in Cell and Developmental Biology

VOLUME=8

YEAR=2020

URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2020.00204

DOI=10.3389/fcell.2020.00204

ISSN=2296-634X

ABSTRACT=<p>Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the airways. This review links environmental factors to host epithelial immunity in airway diseases. Understanding altered homeostasis of the airway epithelium might provide important targets for diagnostics and therapy of chronic airway diseases.</p>