AUTHOR=Durston Antony J. TITLE=Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=7 YEAR=2019 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2019.00257 DOI=10.3389/fcell.2019.00257 ISSN=2296-634X ABSTRACT=

The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity (TC). Here, I focus on the two current competing models based on this premise. Common features and points of dissent are examined and a common model is distilled from what remains. This is an attempt to make sense of the literature.