AUTHOR=Kounakis Konstantinos , Chaniotakis Manos , Markaki Maria , Tavernarakis Nektarios TITLE=Emerging Roles of Lipophagy in Health and Disease JOURNAL=Frontiers in Cell and Developmental Biology VOLUME=7 YEAR=2019 URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2019.00185 DOI=10.3389/fcell.2019.00185 ISSN=2296-634X ABSTRACT=

The term lipophagy is used to describe the autophagic degradation of lipid droplets, the main lipid storage organelles of eukaryotic cells. Ever since its discovery in 2009, lipophagy has emerged as a significant component of lipid metabolism with important implications for organismal health. This review aims to provide a brief summary of our current knowledge on the mechanisms that are responsible for regulating lipophagy and the impact the process has under physiological and pathological conditions.