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CASE REPORT article
Front. Cardiovasc. Med.
Sec. Cardio-Oncology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1559173
This article is part of the Research Topic Case Reports in Cardio-Oncology: 2024 View all 11 articles
Severe Immune-mediated Myocarditis Caused by Sintilimab Combined with Gemcitabine: A Case Report and Literature Review Sintilimab combined with gemcitabine-induced severe Immune-mediated myocarditis:A Case Report and Literature Review
Provisionally accepted- Department of Radiotherapy, Xi 'an Chest Hospital Affiliated to Northwest University, Xi'an city, China
This manuscript focuses on a case of severe immune-mediated myocarditis caused by sintilimab combined with gemcitabine in a lung cancer patient, along with a comprehensive literature review. It delves into the diagnosis, treatment, and underlying mechanisms of this rare but life-threatening complication within the context of lung cancer immunotherapy. Journals specializing in oncology, particularly those covering immunotherapy in lung cancer and its associated adverse events, would be highly suitable. Additionally, medical journals with a focus on cardiology, especially dealing with immune-related cardiac disorders, would also be a good fit. The manuscript's content aligns well with the scope of such journals as it contributes valuable insights into the intersection of cancer treatment and cardiovascular complications, providing crucial information for clinicians in both specialties to enhance patient management and outcomes.
Keywords: Xiaosha Zhou: Conceptualization, Data curation, Formal analysis, Writing -review & editing. Shanshan Zhang: Data curation, Writing -review & editing. Menglu Sun: Data curation, methodology, Writing -original draft. Xiaoyan Zhang: Conceptualization, investigation
Received: 12 Jan 2025; Accepted: 25 Mar 2025.
Copyright: © 2025 Yang, Sun, Zhou, Han, Zhang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Haixia Yang, Department of Radiotherapy, Xi 'an Chest Hospital Affiliated to Northwest University, Xi'an city, China
Xiaoyan Zhang, Department of Radiotherapy, Xi 'an Chest Hospital Affiliated to Northwest University, Xi'an city, China
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